What is CellNetdb

The cellular processes in a cell are achieved by groups of genes acting in concert to shape the cellular responses. Understanding how the gene network organized to mediate genotype-phenotype relationship is fundamental to global insights into the biological functions and disease etiology. CellNetdb is a compendium of cell-type-specific interactome networks across 44 human tumor types spanning over 2 million single cells.


Update
2023.10
Cancers
44


Cells
2.2M
Donors
563


Projects
55
Modules
6




Please refer to the following publication:
Zekun Li, Gerui Liu, Xiaoxiao Yang, Meng Shu, Wen Jin, Yang Tong, Xiaochuan Liu, Yuting Wang, Jiapei Yuan, Yang Yang (2024) An atlas of cell-type-specific interactome networks across 44 human tumor types. Genome Medicine 16(1):30







Tips: Please wait for loading , and then select the Cancer Type and click the "Submit" button.


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Tips: Please wait for loading , and then select the Cancer Type and click the "Submit" button.


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Tips: Please wait for loading , and then select the Cell Type and click the "Submit" button.


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Help

Taxonomy



The taxonomy of cell types across different human cancers or pan-cancer infiltrating immune cells were displayed in this module. By selecting cancer/cell type and marker gene, users could visualize the cell-type taxonomy and gene expression pattern of cell-type maker genes. The cell-type taxonomy is displayed by the UMAP plot and the gene expression pattern is displayed by hexagon bin plot. Users could select the ‘Communication’ panel to view the integrated cell-cell communication. In addition, users could also obtain the number of single cells per cell type from the 'Summary' panel.

CellNet